이런 연구들은 AGEs 와 progression of osteoarthritis 의 직접적인 원인규명은 아직 못함 이는 Willet et al 연구에서도 지적
However, as pointed out by Willet et al, these studies have yet to show a direct causative effect between AGEs and theprogression of osteoarthritis.
본연구에서 다루지 못한것-향후 연구에 떠넘길때
However, this is beyond the scope of this study and should be considered for future work.
Obesity 와 advanced accumulation of the AGEs 가 osteoarthritic phenotype 에 영향 하지만 어떻게 그런지는 알수없음
Both obesity and the advanced accumulation of the AGEs may contribute to the osteoarthritic phenotype; however, the manner of this still remains unclear.
본연구-ajoene는 LKB1을 통해서AMPK를 활성화함, CaMKK는 아님 이는 LKB1가 ajoene에 의해 유도된 AMPK 활성화의 upstream kinase 역할을 한다는 의미로 보여진다.
In the present study, ajoene activated AMPK through LKB1, but not CaMKK, implying that LKB1 many serve as an upstream kinase of AMPK activation elicited by ajoene.