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PBL (Interferon) 2009.03.17 학술팀.

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Presentation on theme: "PBL (Interferon) 2009.03.17 학술팀."— Presentation transcript:

1 PBL (Interferon) 학술팀

2 Interferon (IFN) 척추동물의 면역세포에서 생성되는 단백질
Viruses, Bacterial, Parasites, Tumor cell 등의 침입자에 대응 항바이러스, 항증식, 면역조절기능 외부로부터 JAK, STAT signal pathway를 통해 신호전달 Human Interferon Alpha Human Interferon Beta Human Interferon Gamma

3 Interferon type I Interferon type II Interferon type III
- 세포 표면의 IFN-a receptor (IFNAR)인 IFNAR1, IFNAR2에 결합 - Human IFN-alpha, beta Interferon type II - 세포 표면의 IFN-v receptor (IFNGR)인 IFNGR1, IFNGR2에 결합 - Human IFN-gamma Interferon type III - IL10R2 (CRF2-4), IFNLR1 (CRF2-12) receptor complex를 통해 신호전달

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6 ELISA KITS Interferon ELISA Kit Signal Transduction ELISA Kit
- Interferon alpha A(2a), 2(2b) detection 목적으로 개발 - Multi species, Serum sample ELISA kit Signal Transduction ELISA Kit - ERK, STAT1, STAT3, p38 Cell-Based Assay Kit - Simple, Rapid detection - Cell culture, Serum, Plasma

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8 ANTIBODIES Monoclonal antibody Polyclonal antibody
- ELISA, Flow cytometry, Epitope mapping Polyclonal antibody - Neutralization Interferon receptor reagents

9 INTERFERONS Interferons Cytokines & Growth factors CD antibodies
- IL-2, IL-3, GM-CSF, EPO CD antibodies - IL-1R, B7 (Human, Mouse)

10 PBL 제품 판매 현황

11 Assay designs, Prospec 제품 판매 현황

12 다른 브랜드 제품군 Assay designs Alpco Prospec
- IFN-gamma (Human, Mouse) ELISA kit - Interferon signaling 관련 antibody Alpco - IFN-gamma (Human, Mouse, Rat, Monkey, Porcine) EIA kit - 1X96well, 2X96well, 5X96well Prospec - IFN-alpha, beta, gamma recombinant (Huma, Mouse type)

13 PBL과 R사와 제품군 비교 – ELISA kits

14 PBL과 R사와 제품군 비교 – Antibodies

15 제품의 range가 높아 다양한 범위에서 측정가능
PBL 제품군의 특징 다양한 종과 Sub-type의 제품이 존재 - Human, Rat, Mouse를 비롯한 Porcine, Feline, Canine, Ovine 등 - Interferon alpha A, B2, C, D, F, G, G, 2, 4a, 4b 등 제품의 range가 높아 다양한 범위에서 측정가능 Cytokine, Growth factors, CD antibody

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