Acid Chlorides Using Thionyl Chloride The Conversion of tert-Butyl Esters to Acid Chlorides Using Thionyl Chloride 2015062014 김은진 2015062015 임동주 The Journal of Organic Chemistry February 14, 2017
Index Abstract Introduction Result and Discussion Conclusion Reference
Abstract
Introduction 카복실산 → 산 염화물 매커니즘
Introduction 카복실산 유도체의 상대적 반응성 유기 731쪽 그림 첫번째꺼
Introduction 카복실산 유도체의 상호변환
Optimization of tert-Butyl Ester to Acid Chloride Conditions Result and Discussion Optimization of tert-Butyl Ester to Acid Chloride Conditions
Possible Mechanistic Pathways Result and Discussion Possible Mechanistic Pathways
Ester Selectivity with Optimized tert-Butyl Ester Conditions Result and Discussion Ester Selectivity with Optimized tert-Butyl Ester Conditions
Result and Discussion
Result and Discussion
Result and Discussion piv Fmoc Ts
Result and Discussion
Result and Discussion
Result and Discussion
Result and Discussion
Result and Discussion
Result and Discussion TMS TIPS TBS Bn
Result and Discussion piv Fmoc Ts
Result and Discussion
Conclusion 다양한 기질의 tert- 부틸 에스터를 산 염화물로 전환시키는 간단하고 효율적인 방법을 설명 반응이 산에 의해 촉진된다는 것을 시사하며, 경쟁 실험은 반응이 메틸, 1 °또는 2 °에스터 및 락톤의 존재하에 tert- 부틸 에스터에 대해 선택적임 알켄, 메틸 에터, 보호 된 아민, 설폰산 염, 탄산염 및 아세테이트 그룹을 비롯한 다른 작용기와 호환되며 산 염화물 합성에 일반적으로 사용되는 다른 방법의 대안을 제공
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