진행상황 박노열

Overview 2D – 3D deform matching

Overview 2D – 3D deform matching FNSA : 133.25 FAV : 32.74 Bowing : 7.63 Neck Length : 41.37

Contribution X-ray 이미지만으로 3D shape 재구성 자동으로 clinical measurement 측정 CT에서의 측정보다 더 좋은 결과

Method Learning CT 3D shape PCA Clinical measurement

Method Optimization PCA 3D shape + Optimization Clinical measurement X-ray

Method Optimization PCA Silhouette Search for Closest point 3D distance Target Silhouette Gradient descent method

Data 뇌성마비환자 54명의 3D shape 자동 측정 CM 직접 측정 CM CT로부터 측정된 FNSA, FAV 값

Experiment X-ray 대신 Silhouette 사용 Leave-one-out test SPSS 9가지 각도 2장 , coronal plane, sagittal plane Leave-one-out test SPSS Paired t-test Significance level = 0.2

Experiment X-ray 대신 Silhouette 사용 Leave-one-out test SPSS 9가지 각도 2장 , coronal plane, sagittal plane Leave-one-out test SPSS Paired t-test Significance level = 0.2

Experiment X-ray 대신 Silhouette 사용 Leave-one-out test SPSS 9가지 각도 2장 , coronal plane, sagittal plane Leave-one-out test SPSS Paired t-test Significance level = 0.2

Experiment 자동측정 CM 결과값을 True 직접측정 CM 결과값을 True 자동측정으로 PCA 후 비교

Experiment Optimization 결과와 True값과의 차이에 대한 분포 추정 및 신뢰구간 추정

Result FNSA(deg) FAV(deg) Shaft bowing (deg) Neck length (mm) Avg 2.82 4.21 0.87 1.95 3.74 5.78 Std 2.30 3.26 0.67 1.58 4.08 4.23 Max 11.55 11.43 3.31 6.29 23.68 20.61 Min 0.06 0.07 0.02 0.04 0.12 0.55 3.15 3.90 4.03 5.41 2.37 3.11 4.29 5.18 10.08 12.43 23.96 28.40 0.05 0.08 0.11 3.08 3.84 0.78 2.35 2.44 0.60 2.09 9.62 9.93 2.95 8.86 0.01

Result 평균 표준편차 평균의 표준오차 t 유의확률 (양쪽) FNSA_자동 - FNSA_CT -.91741 4.87832 .66385 -1.382 .173 FAV_자동 - FAV_CT -1.57648 4.53133 .61664 -2.557 .013 -.88370 4.97384 .67685 -1.306 .197 -1.50796 5.99393 .81567 -1.849 .070 FNSA_직접 - FNSA_CT -.87209 4.60431 .62657 -1.392 .170 FAV_직접 - FAV_CT -1.57802 5.41564 .73698 -2.141 .037

Result 평균 표준편차 평균의 표준오차 t 유의확률 (양쪽) FNSA_Coronal - FNSA_CT -1.02537 4.81502 .65524 -1.565 .124 FAV_Coronal - FAV_CT -.25037 5.09831 .69379 -.361 .720 FNSA_Sagittal - FNSA_CT -.04074 5.38420 .73270 -.056 .956 FAV_Sagittal - FAV_CT -.74722 5.11822 .69650 -1.073 .288 -1.06981 4.86123 .66153 .112 -.96370 6.12688 .83376 .253 -.21944 5.53175 .75278 .772 -.47759 6.25390 .85105 .577 -.86870 4.71965 .64226 -1.353 .182 -1.52907 5.42365 .73806 -2.072 .043 -.50019 4.95279 .67399 -.742 .461 -1.56556 5.42208 .73785 -2.122 .039

2장 FNSA avg std max min 밖,앞 2.94 2.55 11.96 0.01 밖 2.91 2.38 11.47 0.34 밖,뒤 3.07 2.29 12.20 0.08 앞 3.13 2.34 10.74 2.86 2.57 14.22 0.07 뒤 3.08 2.36 11.34 0.52 안,앞 3.10 2.72 12.19 0.03 안 2.84 11.54 안,뒤 2.90 2.47 11.80 0.05 FNSA avg std max min 밖,앞 3.01 2.55 9.71 0.01 밖 2.98 2.31 8.28 0.13 밖,뒤 2.97 2.38 9.62 앞 3.35 2.35 9.59 0.05 3.07 2.50 8.97 뒤 3.16 2.19 8.90 0.04 안,앞 3.47 2.41 9.25 0.19 안 3.14 2.25 8.03 안,뒤 3.17 2.29 8.11 FAV avg std max min 밖,앞 4.88 3.80 13.72 0.02 밖 4.80 3.58 15.04 0.07 밖,뒤 4.94 3.39 13.02 앞 4.02 18.22 0.13 4.14 3.52 14.28 0.05 뒤 4.05 3.26 11.68 0.04 안,앞 4.63 2.93 12.06 안 4.33 3.38 12.67 0.10 안,뒤 4.56 13.63 0.40 FAV avg std max min 밖,앞 3.68 2.83 12.42 0.09 밖 3.64 2.28 11.06 0.21 밖,뒤 3.87 2.67 12.86 0.35 앞 3.74 1.95 8.49 0.31 3.75 2.64 11.64 0.03 뒤 3.83 2.22 8.42 0.19 안,앞 3.51 2.50 10.01 0.04 안 3.81 2.60 10.79 0.08 안,뒤 3.67 2.12 8.45

2장 Bowing avg std max min 밖,앞 1.04 0.74 4.23 0.01 밖 1.06 0.78 4.13 0.02 밖,뒤 0.91 0.68 3.49 앞 0.93 0.71 3.32 0.90 0.70 뒤 0.79 0.64 2.65 0.00 안,앞 0.87 2.89 0.09 안 0.83 3.57 0.04 안,뒤 0.84 0.69 2.72 Bowing avg std max min 밖,앞 0.98 0.79 4.71 0.08 밖 1.04 0.82 4.36 0.04 밖,뒤 1.00 0.80 4.04 0.06 앞 0.89 0.69 3.36 0.09 0.68 3.37 0.01 뒤 0.85 0.67 2.76 0.05 안,앞 3.42 안 0.92 0.76 3.86 0.02 안,뒤 0.66 3.73 Length avg std max min 밖,앞 1.98 1.69 6.58 0.02 밖 1.91 1.60 6.12 0.00 밖,뒤 2.06 1.54 5.75 0.01 앞 2.20 1.92 8.12 0.06 1.72 6.86 0.13 뒤 2.23 1.75 7.31 0.12 안,앞 1.59 6.27 0.07 안 2.19 1.51 6.60 0.25 안,뒤 2.26 1.80 6.21 0.11 Length avg std max min 밖,앞 1.99 1.60 7.14 0.02 밖 1.50 6.49 0.06 밖,뒤 1.95 1.42 6.63 0.12 앞 1.98 1.73 9.19 0.08 2.15 1.59 8.98 0.03 뒤 2.08 1.82 9.51 0.09 안,앞 2.22 1.83 9.69 안 2.18 1.93 8.85 0.01 안,뒤 2.21 1.89 7.45

Coronal Plane FNSA avg std max min 밖,앞 3.96 2.66 13.35 0.47 밖 3.65 2.58 10.36 0.02 밖,뒤 3.13 2.64 13.29 0.03 앞 3.97 3.16 12.81 0.09 3.62 2.99 12.61 0.17 뒤 2.62 2.01 8.16 0.01 안,앞 3.59 2.84 13.61 안 3.41 2.92 13.75 0.05 안,뒤 2.69 2.02 9.22 FNSA avg std max min 밖,앞 4.48 3.48 15.05 0.08 밖 4.00 2.59 10.49 0.07 밖,뒤 3.38 2.52 13.52 0.28 앞 4.17 2.66 10.22 0.10 3.87 2.74 11.00 0.01 뒤 3.31 2.47 9.56 0.02 안,앞 3.84 2.61 9.70 0.18 안 3.28 2.55 10.03 안,뒤 2.97 2.31 8.95 FAV avg std max min 밖,앞 5.21 3.71 17.74 0.13 밖 6.02 4.29 16.38 0.04 밖,뒤 5.44 4.57 18.04 0.10 앞 7.73 5.08 23.39 0.33 8.45 6.09 28.05 0.02 뒤 6.24 4.26 20.01 0.59 안,앞 6.74 5.37 22.12 0.06 안 9.76 25.41 0.27 안,뒤 8.60 6.25 26.03 0.31 FAV avg std max min 밖,앞 4.28 2.98 10.90 0.20 밖 4.41 3.27 12.38 0.18 밖,뒤 4.07 2.73 11.41 0.10 앞 4.61 3.15 12.76 0.27 5.37 3.81 15.30 0.23 뒤 4.60 3.44 14.27 안,앞 5.75 4.02 15.96 0.56 안 6.53 4.31 19.58 0.21 안,뒤 4.89 3.80 18.12 0.24

Coronal Plane Bowing avg std max min 밖,앞 1.27 0.95 5.00 0.04 밖 1.87 1.36 5.27 0.07 밖,뒤 1.15 0.85 3.68 0.06 앞 1.34 1.12 6.24 1.80 1.52 7.69 0.02 뒤 1.25 0.96 0.01 안,앞 1.18 1.31 6.25 안 1.75 1.37 5.01 0.00 안,뒤 1.04 5.12 Bowing avg std max min 밖,앞 1.27 1.05 4.99 0.02 밖 1.63 1.23 4.69 0.01 밖,뒤 0.96 4.01 앞 1.46 1.20 4.83 1.95 1.51 8.47 0.21 뒤 1.22 1.01 4.31 안,앞 1.36 1.38 8.36 안 1.47 6.07 안,뒤 1.14 1.17 7.64 Length avg std max min 밖,앞 2.98 2.26 11.25 0.09 밖 2.41 2.11 8.19 0.05 밖,뒤 2.51 2.18 7.88 0.01 앞 2.76 2.15 10.61 0.17 2.67 2.28 11.30 0.06 뒤 2.32 1.90 10.31 0.11 안,앞 2.50 2.03 8.73 0.03 안 2.22 9.49 안,뒤 2.57 2.10 9.22 Length avg std max min 밖,앞 2.78 2.21 10.53 0.00 밖 2.41 2.04 7.45 0.03 밖,뒤 2.33 1.60 6.36 0.01 앞 3.13 2.01 9.08 2.43 1.67 6.24 뒤 2.76 9.03 0.12 안,앞 2.86 2.02 7.94 안 2.53 1.87 8.07 0.07 안,뒤 2.70 2.15 9.49 0.02

Sagittal Plane FNSA avg std max min 밖,앞 3.21 2.62 13.79 0.08 밖 3.49 2.77 13.95 0.10 밖,뒤 3.34 2.86 15.11 0.03 앞 4.20 4.38 26.51 0.05 4.62 28.79 0.06 뒤 4.48 4.32 26.44 안,앞 4.37 3.37 20.98 0.11 안 4.23 3.42 15.12 0.07 안,뒤 4.79 4.18 21.11 0.15 FNSA avg std max min 밖,앞 3.21 2.50 13.19 0.15 밖 3.15 2.58 10.63 0.05 밖,뒤 3.12 2.67 12.64 0.28 앞 4.04 3.52 14.75 0.11 4.02 3.14 13.29 뒤 3.49 13.53 안,앞 4.84 4.61 27.61 0.04 안 4.94 3.90 16.56 안,뒤 4.90 4.47 24.83 0.34 FAV avg std max min 밖,앞 6.29 4.54 20.73 0.45 밖 6.33 4.63 17.92 0.03 밖,뒤 6.25 4.89 19.94 0.02 앞 5.20 4.38 19.30 0.15 5.63 4.32 18.14 0.34 뒤 5.23 4.06 16.86 0.18 안,앞 5.18 3.22 13.80 0.32 안 5.40 3.18 11.95 0.26 안,뒤 4.90 3.50 15.56 0.00 FAV avg std max min 밖,앞 4.57 4.59 22.00 0.04 밖 4.86 4.48 21.65 0.02 밖,뒤 5.32 4.89 21.91 0.24 앞 5.39 3.92 17.07 0.12 5.36 3.44 13.65 0.06 뒤 5.20 3.56 15.33 0.56 안,앞 4.87 3.69 14.38 0.10 안 4.35 3.23 13.08 0.32 안,뒤 4.28 3.48 14.70 0.11

Sagittal Plane Bowing avg std max min 밖,앞 1.03 0.88 4.49 0.02 밖 1.11 0.87 4.51 밖,뒤 0.90 4.22 앞 0.86 0.69 3.01 0.09 0.73 2.86 0.00 뒤 0.81 0.65 2.78 안,앞 0.91 0.66 2.71 0.05 안 0.64 2.52 안,뒤 0.89 2.62 Bowing avg std max min 밖,앞 1.17 1.07 5.35 0.01 밖 1.19 0.94 5.05 0.04 밖,뒤 0.96 4.49 앞 0.95 0.66 2.93 0.06 0.90 0.73 3.35 뒤 0.86 3.20 0.03 안,앞 0.88 0.61 2.52 안 0.91 0.59 2.47 0.05 안,뒤 0.87 0.57 2.53 Length avg std max min 밖,앞 2.57 2.02 8.10 0.06 밖 2.66 7.51 0.02 밖,뒤 2.39 1.70 8.01 0.01 앞 2.61 2.33 10.33 0.12 2.69 2.36 11.15 뒤 2.68 2.29 10.55 0.16 안,앞 2.07 1.84 8.35 0.09 안 2.17 8.74 0.04 안,뒤 2.40 2.00 8.16 0.00 Length avg std max min 밖,앞 2.50 2.34 12.44 0.04 밖 2.56 2.22 11.25 0.09 밖,뒤 2.73 2.47 12.19 0.03 앞 2.88 13.80 0.02 2.60 2.59 11.22 0.00 뒤 2.65 2.38 12.99 0.05 안,앞 2.76 2.25 10.54 0.20 안 2.95 2.29 8.95 0.01 안,뒤 2.86 10.56

예상범위 추정 FNSA FAV Bowing Neck length Avg 0.41 0.05 -0.01 -0.09 Std 3.64 정규성 검정 Kolmogorov-Smirnova Shapiro-Wilk 통계량 자유도 유의확률 FNSA .080 54 .200 .984 .679 FAV .095 .972 .228 Bowing .068 .983 .613 NeckLength .092 .987 .809 FNSA FAV Bowing Neck length Avg 0.41 0.05 -0.01 -0.09 Std 3.64 5.35 1.10 2.52 upper 95% 1.38 1.47 0.28 0.58 lower 95% -0.56 -1.38 -0.31 -0.77

예상범위 추정 FNSA FAV Bowing Neck length Avg -0.20 0.09 -0.07 -0.15 Std 정규성 검정 Kolmogorov-Smirnova Shapiro-Wilk 통계량 자유도 유의확률 FNSA .062 54 .200 .982 .607 FAV .097 .976 .360 Bowing .069 .972 .230 NeckLength .083 .970 .193 FNSA FAV Bowing Neck length Avg -0.20 0.09 -0.07 -0.15 Std 3.78 4.19 1.15 2.53 upper 95% 0.80 1.21 0.24 0.52 lower 95% -1.21 -1.03 -0.38 -0.83

Conclusion 2장으로 Optimization시 더 좋은 결과 Coronal plane만으로도 괜찮은 결과